Friday, May 17, 2013

New prostate cancer drug, Xofigo, gains FDA fast-track approval earlier this week

Only 3 months benefit?  More discouraging than encouraging, don't you think?


Bayer's Xofigo for Prostate Cancer Gets Fast Approval

SILVER SPRING, Md. -- The FDA has approved radium-223 dichloride (Xofigo) for treating bone metastases from castration-resistant prostate cancer, the agency said Wednesday. Its specific indication is for men with symptomatic, late-stage, castration-resistant prostate cancer with metastases in bone but not other organs, following conventional medical and/or surgical therapy to reduce testosterone levels.

The approval was based primarily on a placebo-controlled trial in 809 patients that showed a median overall survival time of 14 months in those receiving the drug compared with 11.2 months in the placebo group. Patients in the trial also received other treatments judged to be clinically appropriate on an individual basis.
Radium-223 dichloride binds chemically to minerals in bone "to deliver radiation directly to bone tumors, limiting the damage to surrounding tissues," said Richard Pazdur, MD, director of the FDA's Office of Hematology and Oncology Products, in a statement.

The approval, made through the agency's priority review process, came 3 months before the FDA's Aug. 14 deadline to render a decision.

Adverse effects seen with the drug in clinical trials included nausea, diarrhea, vomiting, and swelling of the leg, ankle, or foot, the FDA said. Hematologic effects included anemia, lymphocytopenia, leukopenia, thrombocytopenia, and neutropenia.

The drug was developed by Bayer Pharmaceuticals, Wayne, N.J.

Monday, May 6, 2013

Some good news on the celebrity cancer front...

Not sure if he can legitimately claim that pot cured his prostate cancer, but leave it to Tommy to try:

Tommy Chong Prostate Cancer-Free, Comedian Reports

Posted on May 6, 2013 - SFgate.com

Activist and comedian Tommy Chong claims he is cancer-free today on website
Celebstoner.com

“I brought my PSA numbers down drastically and eliminated the cancer threat… That’s right, I kicked cancer’s ass! So the magic plant does cure cancer with the right diet and supplements. I’m due for another blood test, MRI, etc., but I feel the best I’ve felt in years.”

Chong announced last year that he had been diagnosed with prostate cancer, a severe but treatable form or cancer if caught early.  Chong reports avoiding expensive, experimental treatments for dietary change, supplements and hemp oil. 

“With the diet, the supplements and the hash oil, plus a session with a world-renowned healer, Adam Dreamhealer, I’m cancer-free,” he wrote. And now for a celebration joint of the finest Kush.”

Doctors define a cancer treatment as a “cure” if a patient lives five years without the return of the cancer.

Feel good and keep smiling; Tommy is!  Pat